As far as I am able to judge, after long attending to the subject, the conditions of life appear to act in two ways--directly on the whole organisation or on certain parts alone and in directly by affecting the reproductive system.

With respect to the direct action, we must bear in mind that in every case, as Professor Weismann has lately insisted, and as I have incidently shown in my work on "Variation under Domestication," there are two factors: namely, the nature of the organism and the nature of the conditions.

The former seems to be much the more important; for nearly similar variations sometimes arise under, as far as we can judge, dissimilar conditions; and, on the other hand, dissimilar variations arise under conditions which appear to be nearly uniform.